Transcriptomics

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Cabergoline-treated lutein granulosa cells from polycystic ovarian syndrome (PCOS) patients exhibit higher transcriptomic response than cabergoline-treated controls


ABSTRACT: This study assessed the transcriptomic profiles of lutein granulosa cells (LGCs) from women with and without PCOS using Affymetrix microarray chips to provide novel information about the molecular changes that occur in these cells when they are treated with a D2-ag (Cb2) and to assess the signal transduction pathways regulated by this treatment. Transcriptomic analysis, using Affimetrix Human 1.0ST. GeneChip Microarray was functionally analyzed by Gene Set Enrichment Analysis (GSEA) and network modeling with system biology perspective.

ORGANISM(S): Homo sapiens

PROVIDER: GSE98595 | GEO | 2017/09/03

SECONDARY ACCESSION(S): PRJNA385612

REPOSITORIES: GEO

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