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Methyl-Spec-seq control data sets

ABSTRACT: We developed a novel in-vitro experimental method to characterize the protein-DNA interaction specificity and methylation sensitivity, we called Methyl-Spec-seq. In this data set, mouse AP1 was used as a positive control example to show that Methyl-Spec-seq can determine the relative binding energy for variants with different methylation property, i.e., unmethylated, top hemimethylated, bottom hemimethylated, duplex methylated by either chemical synthesis or enzymatic treatment.

ORGANISM(S): synthetic construct

PROVIDER: GSE98669 | GEO | 2017/10/11

SECONDARY ACCESSION(S): PRJNA385858

REPOSITORIES: GEO

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