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Methyl-Spec-seq data for HOXB13

ABSTRACT: We developed a novel in-vitro experimental method to characterize the protein-DNA interaction specificity and methylation sensitivity, we called Methyl-Spec-seq. In this data set, mouse HOXB13 (F1-F3) was used as a positive control example to show that Methyl-Spec-seq can determine the relative binding energy for variants with different methylation property, i.e., unmethylated, top hemimethylated, bottom hemimethylated, duplex methylated by either chemical synthesis or enzymatic treatment.

ORGANISM(S): synthetic construct

PROVIDER: GSE102703 | GEO | 2017/08/17

SECONDARY ACCESSION(S): PRJNA398472

REPOSITORIES: GEO

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