Transcriptomics

Dataset Information

0

Expression data from ovarian cells growing in three dimensional culture (Matrigel) with altered expression of miR-200s


ABSTRACT: It is believed that incessant ovulation will cause formation of ovarian cysts which later lead to ovarian cancer maglinancy. miR-200s is highly expressed in ovarian cancer tissue when compared to ovarian normal tissue. To study wether miR-200s have a pathologenic role in ovarian cyst formation, normal ovarian cells with overexpression of miR-200s and two cancer cell lines with knockdown of miR-200s were grown in a 3D culture system and allowed to form cyst. We used microarrays to detail the global programme of gene expression underlying ovarian cyst formation affected by expression of miR-200s and indentify distinct classes of up-regulated and down-regulated genes during this process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE99217 | GEO | 2018/06/25

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2024-07-03 | GSE250195 | GEO
2011-10-23 | E-GEOD-29988 | biostudies-arrayexpress
2011-10-24 | GSE29988 | GEO
2010-01-31 | E-GEOD-19460 | biostudies-arrayexpress
2023-08-11 | GSE211957 | GEO
2010-02-01 | GSE19460 | GEO
| PRJNA1052653 | ENA
2022-05-02 | GSE186489 | GEO
2020-04-15 | GSE148216 | GEO
2022-07-23 | GSE208647 | GEO