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Kmt2a and Kmt2b Control Memory Function via Different Transcriptional Programs

ABSTRACT: We have analyzed changes in histone 3 lysine 4 methylation (H3K4me) and gene expression resulting either from Kmt2a or Kmt2b knockdown in adult hippocampal CA neurons in mice. We implemented Cre/loxP-mediated conditional knockout strategy in order to knockdown either of these histone methyltransferases in excitatory forebrain neurons in adult mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE99250 | GEO | 2017/06/12

SECONDARY ACCESSION(S): PRJNA387703

REPOSITORIES: GEO

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