Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 120
ORGANISM(S): Danio Rerio (ncbitaxon:7955)
SUBMITTER: Ralph Urbatzka
PROVIDER: MSV000092187 | GNPS | Fri Jun 16 04:18:00 BST 2023
REPOSITORIES: GNPS
European journal of pharmacology 20231026
Obesity is a worldwide epidemic and natural products may hold promise in its treatment. The chlorophyll derivative 13-<sup>2</sup>-hydroxypheophytine (hpa) was isolated in a screen with zebrafish larvae to identify lipid reducing molecules from cyanobacteria. However, the mechanisms underlying the lipid-reducing effects of hpa in zebrafish larvae remain poorly understood. Thus, investigating the mechanism of action of hpa and validation in other model organisms such as mice represents important ...[more]