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GNPS - Physalis crassifolia cultivars for metabolite profiling comparison

ABSTRACT: Set of different cultivars of Physalis crassifolia

INSTRUMENT(S): Orbitrap Exploris 240

ORGANISM(S): Physalis Crassifolia (ncbitaxon:49773)

SUBMITTER: Emerson Ferreira Queiroz

PROVIDER: MSV000092430 | GNPS | Thu Jul 13 07:03:00 BST 2023

REPOSITORIES: GNPS

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Publications

17β-Hydroxy-18-acetoxywithanolides from Aeroponically Grown Physalis crassifolia and Their Potent and Selective Cytotoxicity for Prostate Cancer Cells.

Xu Ya-ming YM Bunting Daniel P DP Liu Manping X MX Bandaranayake Hema A HA Gunatilaka A A Leslie AA

Journal of natural products 20160412 4

When cultivated under aeroponic growth conditions, Physalis crassifolia produced 11 new withanolides (1-11) and seven known withanolides (12-18) including those obtained from the wild-crafted plant. The structures of the new withanolides were elucidated by the application of spectroscopic techniques, and the known withanolides were identified by comparison of their spectroscopic data with those reported. Withanolides 1-11 and 16 were evaluated for their potential anticancer activity using five t ...[more]

PMID: 27071003

Publication: 1/2

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