Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Norie Araki
PROVIDER: PXD007604 | JPOST Repository | Mon Nov 05 00:00:00 GMT 2018
REPOSITORIES: jPOST
Action | DRS | |||
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Data20170214_EF1Amix_IP.wiff | Wiff | |||
Data20170214_EF1Amix_IP.wiff.scan | Wiff | |||
Data20170215_IP_EF1A1_1.wiff | Wiff | |||
Data20170215_IP_EF1A1_1.wiff.scan | Wiff | |||
Data20170215_IP_EF1A1_2.wiff | Wiff |
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Molecular & cellular proteomics : MCP 20181031 2
Neurofibromatosis type 1 (NF1) is an autosomal dominant disease that predisposes individuals to developing benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). The mechanism of NF1-tumorigenesis or the curatives have not been established. Using unique trascriptome and proteome integration method, iPEACH (1), we previously identified translationally controlled tumor protein (TCTP) as a novel biological target for NF1-associated tumors (2). Here, we identified specific TCTP-i ...[more]