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MDCK Culture Medium

ABSTRACT: The SILAC analysis of secreted proteins in monoculture or mix-culture of normal and transformed cells

ORGANISM(S): Cellular Organisms

SUBMITTER: Yasuyuki Fujita

PROVIDER: PXD008209 | JPOST Repository | Wed Nov 14 00:00:00 GMT 2018

REPOSITORIES: jPOST

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			Action	DRS
	20140719_MDCKras_sup01.raw	Raw
	20140719_MDCKras_sup02.raw	Raw
	20140719_MDCKras_sup03.raw	Raw
	20140719_MDCKras_sup04.raw	Raw
	20140719_MDCKras_sup05.raw	Raw

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Publications

ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells.

Yako Yuta Y Hayashi Takashi T Takeuchi Yasuto Y Ishibashi Kojiro K Kasai Nobuhiro N Sato Nanami N Kuromiya Keisuke K Ishikawa Susumu S Fujita Yasuyuki Y

Scientific reports 20180625 1

Recent studies have revealed that newly emerging transformed cells are often eliminated from epithelia via cell competition with the surrounding normal epithelial cells. However, it remains unknown whether and how soluble factors are involved in this cancer preventive phenomenon. By performing stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative mass spectrometric analyses, we have identified ADAM-like Decysin-1 (ADAMDEC1) as a soluble protein whose expression is u ...[more]

PMID: 29941981

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