Effect of the ribonuclease binase on the proteome of A549 cell infected by influenza A(H1N1pdm09) virus
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ABSTRACT: Ribonucleases (RNases) of different origin demonstrate antiviral effects that are mediated by the direct RNase action on RNA species and can also involve signal transduction modulation. To reveal cellular targets and explain the mechanisms underlying the antiviral effect employed by the small extracellular ribonuclease of Bacillus pumilus (binase) both in vitro and in vivo, a shotgun proteomic analysis of influenza A virus (H1N1pdm09)-infected A549 cells upon binase treatment, was performed.
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Raihan Shah Mahmud
PROVIDER: PXD014809 | JPOST Repository | Mon Jul 29 00:00:00 BST 2019
REPOSITORIES: jPOST
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