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The membrane protein profiles from different lung cancer cell lines. The different mutation harboring in different cell line might reflect different phenotype even though they have same cancer type.

ABSTRACT: The membrane proteins are the main receptors that received the signals out of the cells. The abnormal of these membrane proteins will cause the wrong signal transduction which leads to loss of functions or diseases. To fix the abnormal signaling pathways, the intervention of the treatment mostly will target in these membrane receptors to inhibit the abnormal transduction cascade like the tyrosin kinase inhibitors in lung cancer. However, the lung cancer cell line have different kinds of mutation, and each of them have its own unique phenotype and drug response. The study of the membrane protein profiles from these cell lines with different mutation might help to correlate the mutation site and phenotype of the cell lines.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Chia-Li Han

PROVIDER: PXD020587 | JPOST Repository | Mon Jul 27 00:00:00 BST 2020

REPOSITORIES: jPOST

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			Action	DRS
	CL100-1.raw	Raw
	CL100-2.raw	Raw
	CL100-3.raw	Raw
	CL141-1.raw	Raw
	CL141-2.raw	Raw

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