Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Oleg Krokhin
PROVIDER: PXD029416 | JPOST Repository | Sat Dec 10 00:00:00 GMT 2022
REPOSITORIES: jPOST
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Journal of proteome research 20221208 1
Despite the general acceptance of formic acid as the additive of choice for peptide reversed-phase LC-MS/MS applications, some still argue that the selection of acetic acid represents a better option. To settle this debate, we investigated both the difference in MS sensitivity and chromatographic behavior of peptides between these two systems. This interlaboratory study was performed using different MS setups and C18 separation media employing both 0.1% formic and 0.5% acetic acid as ion pairing ...[more]