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Proteomic analysis of bone marrow-derived macrophages of mice treated with recombinant Ssa1, a protein enriched in the hypoxic secretome of Candida albicans.

ABSTRACT: Bone marrow-derived macrophages from mice were treated with recombinant Ssa1, a protein enriched in the hypoxic secretome of Candida albicans.

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Krisana Asano

PROVIDER: PXD046766 | JPOST Repository | Mon Jan 29 00:00:00 GMT 2024

REPOSITORIES: jPOST

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			Action	DRS
	230714_Asano_1-3_IDA.wiff	Wiff
	230714_Asano_1-3_IDA.wiff.scan	Wiff
	230714_Asano_1_SWATH.wiff	Wiff
	230714_Asano_1_SWATH.wiff.scan	Wiff
	230714_Asano_2_SWATH.wiff	Wiff

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Publications

Heat Shock Protein SSA1 Enriched in Hypoxic Secretome of Candida albicans Exerts an Immunomodulatory Effect via Regulating Macrophage Function.

Teng Wei W Subsomwong Phawinee P Narita Kouji K Nakane Akio A Asano Krisana K

Cells 20240110 2

Candida albicans is an opportunistic pathogenic yeast that can survive in both normoxic and hypoxic environments. The involvement of C. albicans secretome on host biological processes has been demonstrated. However, the immunoregulatory function of C. albicans secretome released under hypoxic condition remains unclear. This study demonstrated the differences in cytokine responses and protein profiles between secretomes prepared under normoxic and hypoxic conditions. Furtherm ...[more]

PMID: 38247818

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