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Mechanisms connecting the conserved protein kinases Kin1, Pom1, and Ssp1 in fission yeast cell polarity and division

ABSTRACT: Connections between the protein kinases that function within complex cell polarity networks are poorly understood. Rod-shaped fission yeast cells grow in a highly polarized manner, and genetic screens have identified many protein kinases required for polarized growth and cell shape. Kin1, the sole MARK/PAR-1 family kinase in fission yeast, regulates cell polarity and cytokinesis through unknown mechanisms. We performed a large-scale phosphoproteomics screen to identify and characterize Kin1 substrates in cells.

INSTRUMENT(S): Orbitrap Fusion, Q Exactive Plus

ORGANISM(S): Schizosaccharomyces Pombe (ncbitaxon:4896)

SUBMITTER: Arminja Kettenbach

PROVIDER: MSV000081185 | MassIVE | Thu Jun 22 11:24:00 BST 2017

SECONDARY ACCESSION(S): PXD006782

REPOSITORIES: MassIVE

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Defining how Pak1 regulates cell polarity and cell division in fission yeast

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