Ontology highlight
ABSTRACT:
INSTRUMENT(S): autoflex
ORGANISM(S): Multiple
SUBMITTER: Laura Sanchez Brian Murphy
PROVIDER: MSV000083461 | MassIVE | Mon Feb 18 16:57:00 GMT 2019
REPOSITORIES: MassIVE
Journal of natural products 20190723 8
Libraries of microorganisms have been a cornerstone of drug discovery efforts since the mid-1950s, but strain duplication in some libraries has resulted in unwanted natural product redundancy. In the current study, we implemented a workflow that minimizes both the natural product overlap and the total number of bacterial isolates in a library. Using a collection expedition to Iceland as an example, we purified every distinct bacterial colony off isolation plates derived from 86 environmental sam ...[more]