Proteomics

Dataset Information

0

Minimizing Taxonomic and Natural Product Redundancy in Microbial Libraries Using MALDI-TOF MS and the Bioinformatics Pipeline IDBac


ABSTRACT: This bacterial MALDI-TOF dataset was used for the study "AMinimizing Taxonomic and Natural Product Redundancy in Microbial Libraries Using MALDI-TOF MS and the Bioinformatics Pipeline IDBac" It consists of triplicate MALDI-TOF MS profiles (both reflectron and linear datasets) for >1,600 bacteria cultivated from a collection in Iceland.

INSTRUMENT(S): autoflex

ORGANISM(S): Multiple

SUBMITTER: Laura Sanchez   Brian Murphy  

PROVIDER: MSV000083461 | MassIVE | Mon Feb 18 16:57:00 GMT 2019

REPOSITORIES: MassIVE

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1
altmetric image

Publications

Minimizing Taxonomic and Natural Product Redundancy in Microbial Libraries Using MALDI-TOF MS and the Bioinformatics Pipeline IDBac.

Costa Maria S MS   Clark Chase M CM   Ómarsdóttir Sesselja S   Sanchez Laura M LM   Murphy Brian T BT  

Journal of natural products 20190723 8


Libraries of microorganisms have been a cornerstone of drug discovery efforts since the mid-1950s, but strain duplication in some libraries has resulted in unwanted natural product redundancy. In the current study, we implemented a workflow that minimizes both the natural product overlap and the total number of bacterial isolates in a library. Using a collection expedition to Iceland as an example, we purified every distinct bacterial colony off isolation plates derived from 86 environmental sam  ...[more]

Similar Datasets

| PRJEB50468 | ENA
| PRJEB47832 | ENA
2024-06-10 | MSV000094968 | MassIVE
| PRJEB43543 | ENA
| PRJEB45445 | ENA
2024-10-24 | PXD057138 |
2019-04-09 | PXD012519 | Pride
2024-06-10 | MSV000094968 | GNPS
2021-04-21 | PXD022404 | Pride
2021-12-28 | PXD030653 |