Gonatopoulos-Pournatzis _eIF4Gmicroexon_P105_Lumos

ABSTRACT: A This dataset consists of 24 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition mode. B Mouse samples were generated by Thomas Gonatopoulos-Pournatzis. Proteomics sample preparation and mass spectrometric acquisition was performed by Shen Zhang. Analysis was performed by Shen Zhang and Robert J. Weatheritt. C The files are associated with a manuscript submitted for publication by Thomas Gonatopoulos-Pournatzis et al. The main goal of this paper was to reveal a critical role for alternative splicing in the functional specialization of the translational machinery, and further uncover an autism-disrupted mechanism by which microexons reprogram the synaptic proteome to control neuronal activity and higher-order cognitive functions. D Benjamin J. Blencowe ([e-mail]), Sabine P. Cordes ([e-mail]) and Thomas Gonatopoulos-Pournatzis ([e-mail]) are the corresponding authors of the manuscript; Anne-Claude Gingras should be contacted for questions on this dataset ([e-mail]). This submission is associated with 2 Supplementary Files (in addition to this README file) Table 1 describes the composition of this dataset Table 2 lists all the protein and peptide identification evidence

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (ncbitaxon:10090)

SUBMITTER: Anne-Claude Gingras  

PROVIDER: MSV000084658 | MassIVE | Wed Dec 04 14:17:00 GMT 2019

REPOSITORIES: MassIVE