Cowen_Myers_Chemogenomics_2021
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 6600
ORGANISM(S): Candida Albicans (ncbitaxon:5476)
SUBMITTER: 
Anne-Claude Gingras
PROVIDER: MSV000088204 | MassIVE | Fri Oct 08 05:41:00 BST 2021
SECONDARY ACCESSION(S): PXD029002
REPOSITORIES: MassIVE
Similar Datasets
Project description:This dataset consists of 37 raw MS files and associated peak lists and result files, acquired on TripleTOF6600 mass spectrometer operated in Data Dependent Acquisition mode. The files are associated with a manuscript submitted for publication by Segal et al. that determines the protein-protein and proximity interaction landscape of 14-3-3 proteins.
This particular dataset consists in files associated with three baits (14-3-3 interactors) profiled in both a wild type and a 14-3-3 binding site mutant. Each bait was profiled in biological duplicates by BioID (*using the BioID2 enzyme), alongside a total of 25 negative controls (used for analysis with SAINTexpress). See details within the README file.
Samples were generated by Dmitri Segal and affinity purification and mass spectrometry were performed by Zhen-Yuan Lin with oversight from Brett Larsen and Anne-Claude Gingras. Analysis was performed by Anne-Claude Gingras and Mikko Taipale.
Corresponding authors: Mikko Taipale (mikko.taipale@utoronto.ca)/lead author and Anne-Claude Gingras (gingras@lunenfeld.ca). Anne-Claude Gingras should be contacted for questions on this dataset.
2022-05-07 | MSV000089437 | MassIVE
Project description:This dataset consists of 22 raw MS files and associated peak lists and result files, acquired on Velos Orbitrap and TripleTOF mass spectrometers operated in Data Dependent Acquisition mode. The AJUBA construct and cell line were generated by Bhavisha Rathod, with mass spectrometric acquisition by Zhen-Yuan Lin. Data analysis was performed by Anne-Claude Gingras. The files are associated with a manuscript submitted for publication by Loganathan et al. that describes the identification of the NOTCH pathway as a critical regulator of Squamous Cell Carcinoma. Daniel Schramek is the corresponding author of the manuscript (schramek@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca).
2019-02-05 | MSV000083405 | MassIVE
Project description:This dataset consists of 18 raw MS files and associated peak lists and result files, acquired on AB SCIEX 5600 TripleTOF mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Michael Aregger, affinity purification and mass spectrometric acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Anne-Claude Gingras, Cassandra Wong and Zhen-Yuan Lin.
The files are associated with a manuscript submitted for publication by Michael Aregger et al. The main goal of this paper was to systematically map genetic interactions for de novo fatty acid synthesis
Jason Moffat is the corresponding author of the manuscript (j.moffat@utoronto.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca).
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
2020-02-25 | MSV000085005 | MassIVE
Project description:This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 5600 mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Yichao Zhao. Immunoprecipitation and mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Yichao Zhao, Zhen-Yuan Lin, Anne-Claude Gingras and Daniel Durocher.
The files are associated with a manuscript submitted for publication by Yichao Zhao et al. The main goal of this paper was to identify genes that suppress DNA damage in human cells. This dataset comprehensively maps the interactome of GNB1L using proximity labeling coupled to affinity purification.
Daniel Durocher is the corresponding author of the manuscript (durocher@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
2023-06-15 | MSV000092177 | MassIVE
Project description:This dataset consists of 12 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 5600 mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Yichao Zhao. Immunoprecipitation and mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Yichao Zhao, Zhen-Yuan Lin, Anne-Claude Gingras and Daniel Durocher.
The files are associated with a manuscript submitted for publication by Yichao Zhao et al. The main goal of this paper was to identify genes that suppress DNA damage in human cells. This dataset comprehensively maps the interactome of GNB1L using proximity labeling coupled to affinity purification.
Daniel Durocher is the corresponding author of the manuscript (durocher@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
2023-06-15 | MSV000092179 | MassIVE
Project description:This dataset consists of 16 raw MS files and associated peak lists and result files, acquired on a TripleTOF 5600 (AB SCIEX, Concord, ON, Canada) mass spectrometer operated in Data Independent Acquisition mode (SWATH). Samples were generated by the lab group of Arnim Pause and streptavidin pulldowns and mass spectrometric acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Claire Martin and Anne-Claude Gingras. The files are associated with a manuscript submitted for publication by Kazan et al. in which endofin and HD-PTPs complimentary functions in receptor-mediated endocytosis and lysosomal degradation is investigated. Arnim Pause is the corresponding author of the manuscript (arnim.pause@mcgill.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca).
2021-06-25 | MSV000087705 | MassIVE
Project description:This dataset consists of 6 raw MS files and associated peak lists and results files, acquired on Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by YiQing Lu. BioID and Mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was performed by YiQing Lu, Anne-Claude Gingras, and Daniel Schramek.
The files are associated with a manuscript submitted for publication by YiQing Lu et al. The main goal of this paper was to identify novel interactors of wild-type and p53 mutants commonly found in cancer. This dataset profiles the interactomes of C16orf72 in U2-OS cells.
Daniel Schramek is the corresponding author of the manuscript (schramek@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
2023-12-11 | MSV000093632 | MassIVE
Project description:This dataset consists of 6 raw MS files and associated peak lists and results files, acquired on Orbitrap Elite mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by YiQing Lu. BioID and Mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was performed by YiQing Lu, Anne-Claude Gingras, and Daniel Schramek.
The files are associated with a manuscript submitted for publication by YiQing Lu et al. The main goal of this paper was to identify novel interactors of wild-type and p53 mutants commonly found in cancer. This dataset profiles the interactomes of C16orf72 in HEK293 cells.
D
Daniel Schramek is the corresponding author of the manuscript (schramek@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
2023-12-11 | MSV000093630 | MassIVE
Project description:This dataset consists of 15 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode.
Samples were generated by Camila Aprosoff. FLAG-AP and Mass spectrometry acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Cassandra Wong and Boris Dyakov.
The files are associated with a manuscript submitted for publication by Camila Aprosoff et al. The main goal of this paper was to investigate SLX4 as a scaffold for DNA repair and chromatin-associated proteins. This dataset comprehensively maps the interactome of SLX4 using proximity labeling and affinity purification.
Anne-Claude Gingras is the corresponding author of the manuscript (gingras@lunenfeld.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca)
This submission is associated with 3 Supplementary Files (in addition to this README file)
Table 1 describes the composition of this dataset
Table 2 lists all the peptide identification evidence (as per iProphet)
Table 3 lists the SAINTexpress interactions
| MSV000090314 | MassIVE
Project description:This dataset consists of 14 raw MS files and associated peak lists and result files, acquired on LTQ-Orbitrap Velos (Thermo Electron) mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by the lab group of Arnim Pause and affinity purification and mass spectrometric acquisition was performed by Zhen-Yuan Lin. Analysis was performed by Nicole St-Denis. The files are associated with a manuscript submitted for publication by Kazan et al. in which endofin and HD-PTPs complimentary functions in receptor-mediated endocytosis and lysosomal degradation is investigated. Arnim Pause is the corresponding author of the manuscript (arnim.pause@mcgill.ca); Anne-Claude Gingras should be contacted for questions on this dataset (gingras@lunenfeld.ca).
2021-06-25 | MSV000087704 | MassIVE