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TIMSFolding allows the use of ion mobility enhanced spectral libraries

ABSTRACT: Files associated with the TIMSFolding preprint V1 and associated program. K562 lysates on 2 hour runs were used to generate 2 spectral libraries, the first with the native data and the second with the 1/k0 value of the corresponding spectra "folded" into the MGF spectra. We describe both the compatibility of TIMSFolded ion mobility MS/MS data with multiple search tools and demonstrate the use of the folded 1/k0 value as an additional confidence metric in peptide spectral match assignment

INSTRUMENT(S): timsTOF fleX

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Benjamin Orsburn

PROVIDER: MSV000088290 | MassIVE | Sun Oct 31 09:53:00 GMT 2021

SECONDARY ACCESSION(S): PXD029447

REPOSITORIES: MassIVE

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