Dataset Information

Proteomic evaluation of decellularization of porcine auricular cartilage

ABSTRACT: This dataset represents protein profiles of porcine ear cartilage before and after decellularization.

INSTRUMENT(S): LTQ Velos

ORGANISM(S): Sus Scrofa Domesticus (ncbitaxon:9825)

SUBMITTER: Julia Thom Oxford

PROVIDER: MSV000093673 | MassIVE | Fri Dec 15 13:09:00 GMT 2023

REPOSITORIES: MassIVE

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Publications

Decellularized Porcine Cartilage Scaffold; Validation of Decellularization and Evaluation of Biomarkers of Chondrogenesis.

Stone Roxanne N RN Frahs Stephanie M SM Hardy Makenna J MJ Fujimoto Akina A Pu Xinzhu X Keller-Peck Cynthia C Oxford Julia Thom JT

International journal of molecular sciences 20210609 12

Osteoarthritis is a major concern in the United States and worldwide. Current non-surgical and surgical approaches alleviate pain but show little evidence of cartilage restoration. Cell-based treatments may hold promise for the regeneration of hyaline cartilage-like tissue at the site of injury or wear. Cell-cell and cell-matrix interactions have been shown to drive cell differentiation pathways. Biomaterials for clinically relevant applications can be generated from decellularized porcine auric ...[more]

PMID: 34207917

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