Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Liver
SUBMITTER: Isabel Karkossa
LAB HEAD: Kristin Schubert
PROVIDER: PXD019973 | Pride | 2021-01-04
REPOSITORIES: Pride
Action | DRS | |||
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ExperimentalDesign.xlsx | Xlsx | |||
Leber_Aachen_10.mgf | Mgf | |||
Leber_Aachen_10.raw | Raw | |||
Leber_Aachen_11_181105191311.mgf | Mgf | |||
Leber_Aachen_11_181105191311.raw | Raw |
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Streidl Theresa T Karkossa Isabel I Segura Muñoz Rafael R RR Eberl Claudia C Zaufel Alex A Plagge Johannes J Schmaltz Robert R Schubert Kristin K Basic Marijana M Schneider Kai Markus KM Afify Mamdouh M Trautwein Christian C Tolba René R Stecher Bärbel B Doden Heidi L HL Ridlon Jason M JM Ecker Josef J Moustafa Tarek T von Bergen Martin M Ramer-Tait Amanda E AE Clavel Thomas T
Gut microbes 20210101 1
<i>Extibacter muris</i> is a newly described mouse gut bacterium which metabolizes cholic acid (CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence metabolic and inflammatory responses, few <i>in vivo</i> models exist for studying their metabolism and impact on the host. Mice were colonized from birth with the simplified community Oligo-MM<sup>12</sup> with or without <i>E. muris</i>. As the metabolism of bile acids is known to affect lipid homeostasis, mice were ...[more]