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Ward_2024_VS1_ Mapping C. difficile TcdB interactions with host proteins by BioID

ABSTRACT: This dataset consists of 41 raw mass spectrometry files and associated peak lists and results files, acquired on a Thermo Orbitrap Exploris 480 operated in Data-Dependent Acquisition mode. Protein affinity purification was performed by Jennifer Ward, while Jennifer Ward and John Tam generated samples. Mass spectrometric acquisition was performed by Karl Schreiber. Analysis was performed by Jennifer Ward, Karl Schreiber, Ji-Young Youn, and Roman Melnyk. The files are associated with a manuscript by Jennifer Ward et al. that uses proximity-dependent biotinylation approaches to identify host targets of Diphtheria Toxin (DT) and the Clostridioides difficile toxin B (TcdB). Roman Melnyk is the corresponding author for the manuscript and should be contacted for questions regarding this dataset (roman.melnyk@sickkids.ca).

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

SUBMITTER: Ji-Young Youn

PROVIDER: MSV000096003 | MassIVE | Tue Oct 01 10:36:00 BST 2024

SECONDARY ACCESSION(S): PXD056431

REPOSITORIES: MassIVE

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