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Untargetted lipidomics dataset: LC-MS analysis in two postmortem brain areas of healthy individuals and schizophrenia patients.

ABSTRACT:

Schizophrenia is a common mental illness. It is a complex disorder with many symptoms and cognitive impairments. Despite extensive study, the molecular mechanisms of this disease are still unknown. Present time studies on the lipid composition of the human brain are extremely fragmented. Of the possible levels of molecular analysis involving gene expression at the RNA or protein level, and the representation of polar metabolites and lipids, the latter seem to us to be the most promising now. We chose lipids as representative data of the pathogenic mechanism because they are the main structural components of brain cell tissue. The dataset provided unique samples of lipid LC-MS profiles of post-mortem human brains. Samples include not only healthy individuals but also patients with schizophrenia.

INSTRUMENT(S): Liquid Chromatography MS - negative - reverse phase, Liquid Chromatography MS - positive - reverse phase

SUBMITTER: Olga Bukato

PROVIDER: MTBLS8955 | MetaboLights | 2024-06-04

REPOSITORIES: MetaboLights

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			Action	DRS
	MTBLS8955	Other
	FILES	Other
	a_MTBLS8955_LC-MS_negative_reverse-phase_metabolite_profiling.txt	Txt
	a_MTBLS8955_LC-MS_positive_reverse-phase_metabolite_profiling.txt	Txt
	i_Investigation.txt	Txt

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