Metabolomics

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Necrotizing soft-tissue infections (NSTIs) metabolomics


ABSTRACT: Necrotizing soft-tissue infections (NSTIs) have multiple causes, risk factors, anatomical locations, and pathogenic mechanisms. In patients with NSTI, circulating metabolites may serve as substrate having impact on bacterial adaptation at the site of infection. Metabolic signatures associated with NSTI may reveal potential be useful as diagnostic and prognostic markers, as well as novel targets for therapy. This study used untargeted metabolomics analyses of plasma from NSTI patients (n=34) and healthy (non-infected) controls (n=24) to identify the metabolic signatures and connectivity patterns among metabolites associated with NSTI.

ORGANISM(S): Human Homo Sapiens

TISSUE(S): Blood

DISEASE(S): Necrotizing Soft-tissue Infections

SUBMITTER: Saccenti Edoardo  

PROVIDER: ST001270 | MetabolomicsWorkbench | Mon Oct 28 00:00:00 GMT 2019

REPOSITORIES: MetabolomicsWorkbench

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