Metabolomics

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Dual RNA regulator VcdRP in V. cholerae modulates central metabolism


ABSTRACT: Bacterial small RNAs (sRNAs) are well-known to modulate gene expression by base-pairing with trans-coded transcripts and are typically considered to be non-coding. However, several sRNAs have been reported to also contain an open reading frame and thus are considered dual-function regulators. We discovered a dual-function regulator from Vibrio cholerae, called VcdRP, harboring a 29 amino acid protein (VcdP), as well as a base-pairing sequence. In this study, we measured the metabolite abundance of glycolytic and citric acid cycle intermediates using LC-MS.

ORGANISM(S): Vibrio Cholerae V. Cholerae

TISSUE(S): Bacterial Cells

SUBMITTER: Beatrice Engelmann  

PROVIDER: ST001752 | MetabolomicsWorkbench | Wed Apr 14 00:00:00 BST 2021

REPOSITORIES: MetabolomicsWorkbench

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