Metabolomics

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Resistance to NaFAc of in vitro maturated Toxoplasma gondii bradyzoites in human myotubes.


ABSTRACT: The apicomplexan parasite Toxoplasma gondii forms bradyzoite-containing tissue cysts that cause chronic and drug-tolerant infections. Here, we developed a human myotube-based in vitro culture model of functionally mature tissue cysts. In contrast to fast replicating tachyzoite forms of T. gondii these tissue cysts tolerate exposure to the aconitase inhibitor sodium fluoroacetate. These data characterize bradyzoites and tachyzoites treated with NaFAc.

ORGANISM(S): Toxoplasma Gondii

TISSUE(S): Myotubes

DISEASE(S): Parasitic Infection

SUBMITTER: Martin Blume  

PROVIDER: ST002053 | MetabolomicsWorkbench | Fri Jan 07 00:00:00 GMT 2022

REPOSITORIES: MetabolomicsWorkbench

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