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RNA-Seq analysis of human intact and damaged osteoarthrtitic cartilage following total knee replacement.

ABSTRACT: RNA-Seq analysis of human intact and damaged osteoarthrtitic cartilage following total knee replacement.

PROVIDER: PRJEB12436 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	ERR1223330_1.fastq.gz	Fastqsanger.gz
	ERR1223330_2.fastq.gz	Fastqsanger.gz
	ERR1223340_1.fastq.gz	Fastqsanger.gz
	ERR1223340_2.fastq.gz	Fastqsanger.gz
	ERR1223321_1.fastq.gz	Fastqsanger.gz

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RNA-Seq analysis of human intact and damaged osteoarthrtitic cartilage following total knee replacement.

Project description:This experiment captures the expression of genes between two sites of human cartilage within the same patients to allow investigation of genomic responses to damage during osteoarthritis. Eight patients with symptomatic OA undergoing total knee replacement (n=8, age range 65-79 years, mean age 70.3) were used in this study. Cartilage from paired osteochondral samples were isolated from the intact PLC (posterior lateral condyle) and the damaged DMC (distal medial condyle) for RNA-seq analysis.

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RNA-Seq analysis of human osteoarthritic intact cartilage following total knee replacement

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