Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Bordetella parapertussis and bacteriemia

ABSTRACT: Bordetella parapertussis isolate collected from bacteriemia

PROVIDER: PRJEB29316 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	ERR2854573_1.fastq.gz	Fastqsanger.gz
	ERR2854573_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Transcription profile of dendritic cell line D1 treated with Bordetella Parapertussis

Project description:D1 dendritic cells have been treated with Bordetella Parapertussis (MOI 1:75) on different time points: 4h, 8h, 12h, 24h

2012-03-28 | E-MEXP-3160 | biostudies-arrayexpress

Comparative genomic hybridization of Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains

Project description:Comparative genome hybridization (CGH) of sample of 58 Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains selected to span four clusters as defined by MLST.

2005-12-31 | E-TABM-32 | biostudies-arrayexpress

Comparative genomic hybridization of 71 Bordetella parapertussis strains isolated from humans and sheep

Project description:Comparative genomic hybridization (CGH) of 71 Bordetella parapertussis strains isolated from either humans or sheep, and 1 B. bronchiseptica strain isolated from a rabbit

2006-09-04 | E-TABM-94 | biostudies-arrayexpress

Bordetella parapertussis shotgun proteomic analysis reveals physiological response to iron starvation and potential new virulence determinants absent in Bordetella pertussis

Project description:To our knowledge, we provide the first proteomics study of Bordetella parapertussis, one of the causative agents of whooping cough. We compared the identified proteins different to Bordetella pertussis, the other pathogen causing whooping cough. In addition, we extended the study to investigate the proteome response to iron limitation, a stress condition the pathogens face while infection.

2020-02-05 | PXD012309 | Pride

Whole genome sequences of Bordetella parapertussis isolates collected in France

Project description:Whole genome sequences of Bordetella parapertussis isolates collected in France

| PRJEB45017 | ENA

Bordetella parapertussis strain:KACC 11942

Project description:Bordetella parapertussis strain:KACC 11942 Genome sequencing and assembly

| PRJNA484648 | ENA

Transcriptional profiling of Bordetella hinzii clinical isolates

Project description:Transcriptome analysis of Bordetella hinzii isolates from chronic infection in a human host with interleukin-12 receptor deficiency

2021-09-03 | GSE181542 | GEO

Bordetella parapertussis Circumvents Neutrophil Extracellular Bactericidal Mechanisms.

Project description:B. parapertussis is a whooping cough etiological agent with the ability to evade the immune response induced by pertussis vaccines. We previously demonstrated that in the absence of opsonic antibodies B. parapertussis hampers phagocytosis by neutrophils and macrophages and, when phagocytosed, blocks intracellular killing by interfering with phagolysosomal fusion. But neutrophils can kill and/or immobilize extracellular bacteria through non-phagocytic mechanisms such as degranulation and neutrophil extracellular traps (NETs). In this study we demonstrated that B. parapertussis also has the ability to circumvent these two neutrophil extracellular bactericidal activities. The lack of neutrophil degranulation was found dependent on the O antigen that targets the bacteria to cell lipid rafts, eventually avoiding the fusion of nascent phagosomes with specific and azurophilic granules. IgG opsonization overcame this inhibition of neutrophil degranulation. We further observed that B. parapertussis did not induce NETs release in resting neutrophils and inhibited NETs formation in response to phorbol myristate acetate (PMA) stimulation by a mechanism dependent on adenylate cyclase toxin (CyaA)-mediated inhibition of reactive oxygen species (ROS) generation. Thus, B. parapertussis modulates neutrophil bactericidal activity through two different mechanisms, one related to the lack of proper NETs-inducer stimuli and the other one related to an active inhibitory mechanism. Together with previous results these data suggest that B. parapertussis has the ability to subvert the main neutrophil bactericidal functions, inhibiting efficient clearance in non-immune hosts.

| S-EPMC5240980 | biostudies-literature

Polymorphism of repeated regions of pertactin in Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica.

Project description:Pertactin is an outer membrane protein expressed by Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica that induces protective immunity to Bordetella infections. The immunodominant and immunoprotective epitopes of pertactin include two repeated regions, I and II. Comparison of these two repeated regions showed that B. parapertussis pertactin is invariant, whereas B. pertussis pertactin varies mostly in region I and B. bronchiseptica pertactin varies in both repeated regions I and II, but mostly in region II. These differences may result from specific characteristics of these Bordetella species.

| S-EPMC98445 | biostudies-literature

Comparative genomic hybridization of 12 Bordetella holmesii strains compared to Bordetella pertussis

Project description:Comparative genome hybridization (CGH) of a sample of 12 Bordetella holmesii strains compared to Bordetella pertussis Tohama I

2006-06-30 | E-TABM-55 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data