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Comparative genomic hybridization of 12 Bordetella holmesii strains compared to Bordetella pertussis

ABSTRACT: Comparative genome hybridization (CGH) of a sample of 12 Bordetella holmesii strains compared to Bordetella pertussis Tohama I

INSTRUMENT(S): Scanning hardware

ORGANISM(S): Bordetella pertussis

SUBMITTER: Craig Cummings 

PROVIDER: E-TABM-55 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Characterization of a highly conserved island in the otherwise divergent Bordetella holmesii and Bordetella pertussis genomes.

Diavatopoulos D A DA   Cummings C A CA   van der Heide H G J HG   van Gent M M   Liew S S   Relman D A DA   Mooi F R FR  

Journal of bacteriology 20061013 24

The recently discovered pathogen Bordetella holmesii has been isolated from the airways and blood of diseased humans. Genetic events contributing to the emergence of B. holmesii are not understood, and its phylogenetic position among the bordetellae remains unclear. To address these questions, B. holmesii strains were analyzed by comparative genomic hybridization (CGH) to a Bordetella pertussis microarray and by multilocus sequence typing. Both methods indicated substantial sequence divergence b  ...[more]

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