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Comparative genomic hybridization of Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains


ABSTRACT: Comparative genome hybridization (CGH) of sample of 58 Bordetella bronchiseptica, B. pertussis, and B. parapertussis strains selected to span four clusters as defined by MLST.

INSTRUMENT(S): Scanning hardware

ORGANISM(S): Bordetella pertussis

SUBMITTER: Craig Cummings 

PROVIDER: E-TABM-32 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Bordetella pertussis, the causative agent of whooping cough, evolved from a distinct, human-associated lineage of B. bronchiseptica.

Diavatopoulos Dimitri A DA   Cummings Craig A CA   Schouls Leo M LM   Brinig Mary M MM   Relman David A DA   Mooi Frits R FR  

PLoS pathogens 20051230 4


Bordetella pertussis, B. bronchiseptica, B. parapertussis(hu), and B. parapertussis(ov) are closely related respiratory pathogens that infect mammalian species. B. pertussis and B. parapertussis(hu) are exclusively human pathogens and cause whooping cough, or pertussis, a disease that has resurged despite vaccination. Although it most often infects animals, infrequently B. bronchiseptica is isolated from humans, and these infections are thought to be zoonotic. B. pertussis and B. parapertussis(h  ...[more]

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