Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Paracoccidioides

ABSTRACT: Paracoccidioides sp. overview

PROVIDER: PRJNA297382 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13978777.fastq.gz	Fastqsanger.gz
	SRR13978778.fastq.gz	Fastqsanger.gz
	SRR13978779.fastq.gz	Fastqsanger.gz
	SRR13978780.fastq.gz	Fastqsanger.gz
	SRR13978781.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 7

Similar Datasets

Paracoccidioides response to antifungal argentilactone

Project description:The proteomic profile of the fungus Paracoccidioides sp. was analyzed during incubation with argentilactone. This compound presents a

2015-10-02 | PXD002285 | Pride

Paracoccidioides brasiliensis

Project description:Paracoccidioides brasiliensis Raw sequence reads

| PRJNA322632 | ENA

Transcription profiling of mycelium and yeast cells of Paracoccidioides brasiliensis

Project description:Identification of differential mRNAs produced in the mycelium and yeast cells of Paracoccidioides brasiliensis

2004-04-28 | E-MEXP-103 | biostudies-arrayexpress

Transcriptional Remodeling Patterns in Murine Dendritic Cells Infected with Paracoccidioides brasiliensis: More Is Not Necessarily Better

Project description:Examination and comparison of the transcriptional profile of bone marrow derived dendritic cells (BMDCs) in response to infection by the fungus Paracoccidioides brasiliensis in resistant/susceptible mice

2020-11-25 | GSE158289 | GEO

Paracoccidioides lutzii Pb01

Project description:Paracoccidioides lutzii Pb01 Raw sequence reads

| PRJNA487537 | ENA

Paracoccidioides lutzii Pb01

Project description:Paracoccidioides lutzii Pb01 Transcriptome or Gene expression

| PRJNA506281 | ENA

Paracoccidioides brasiliensis strain:PbCNH

Project description:Paracoccidioides brasiliensis strain:PbCNH Genome sequencing

| PRJNA252732 | ENA

Proteomics reveals virulence-related proteins in Paracoccidioides brasiliensis and Paracoccidioides lutzii yeast cells grown in the presence of L-dihydroxyphenylalanine

Project description:Species of the genus Paracoccidioides cause a systemic infection in human patients. Yeast cells of Paracoccidioides spp. produce melanin in the presence of L-dihydroxyphenylalanine and during infection, which may impact the pathogen survival into the host. To better understand the metabolic changes that occur in melanized Paracoccidioides spp. cells, a proteomic approach was performed to compare melanized and non-melanized Paracoccidioides brasiliensis and Paracoccidioides lutzii yeast cells. Melanization was conducted using L-dihydroxyphenylalanine as a precursor and quantitative proteomics was performed using reversed-phase chromatography coupled to high resolution mass spectrometry. When comparing melanized versus non-melanized cells, 999 and 577 differentially abundant proteins were identified for P. brasiliensis and P. lutzii, respectively. Functional enrichment and comparative analysis revealed 30 abundant biological processes in melanized P. brasiliensis and 18 in P. lutzii, while non-melanized cells from these species had 21 and 25 differentially abundant processes, respectively. Melanized cells presented abundance of other virulence-associated proteins, such as phospholipase, proteases, superoxide dismutase, heat-shock proteins, as well as proteins related to cell-wall remodeling and vesicular transport. The results suggest that L-dihydroxyphenilalanine increases virulence of Paracoccidioides spp. through a complex mechanism involving not only melanin, but other virulence factors as well.

2021-01-20 | PXD021711 | Pride

Paracoccidioides brasiliensis

Project description:Global modulation of gene expression in Paracoccidioides brasiliensis in response to thioridazine

| PRJNA178604 | ENA

Paracoccidioides brasiliensis

Project description:Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing the Mycelium-to-Yeast transition

| PRJNA92775 | ENA