Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Enterovirus

ABSTRACT: Exploring a prolonged enterovirus C104 infection in a severely ill patient using nanopore sequencing

PROVIDER: PRJNA768768 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR16204464_1.fastq.gz	Fastqsanger.gz
	SRR16204465_1.fastq.gz	Fastqsanger.gz
	SRR16204466_1.fastq.gz	Fastqsanger.gz
	SRR16204467_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 4 of 4

Similar Datasets

Effects of Monocyte/Macrophages on the Severity of Hand, Foot, and Mouth Disease Patients due to Enterovirus

Project description:To elucidate alterations in immune cells during enterovirus 71 (EV-A71) infection and explore potential interaction mechanisms.Single-cell sequencing technology was used to sequence peripheral blood monocytes (PBMCs) obtained from a severe hand, foot and mouth disease (HFMD) patient due to EV-A71 and a healthy control.

2024-06-20 | GSE269965 | GEO

Scavenger receptor B2 is a cellular receptor for enterovirus 71

Project description:Enterovirus 71 (EV71) belongs to human enterovirus species A of the genus Enterovirus within the family Picornaviridae. We established transformant cells by transfection of mouse cells with genomic DNA from human cells and then detected two EV71-susceptible cell lines. Using microarray with the two cell lines we found that scavenger receptor B2 is a cellular receptor for EV71.

2009-06-21 | GSE16358 | GEO

Infection with Enterovirus 71 induces modulation of the microRNA profile of the mouse brain

Project description:To further understand the molecular pathogenesis of Enterovirus 71 infection, we profiled cellular microRNAs of brain tissue from suckling Kunming mice infected with EV71 and uninfected mice as comparison.

2016-10-23 | GSE89070 | GEO

Enterovirus

Project description:Enterovirus Raw sequence reads

| PRJNA307310 | ENA

Pathological Features of Enterovirus 71-associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analyses

Project description:Enterovirus 71 (EV71), a member of the Enterovirus genus in the Picornaviridae family, was first recognized as a dermotrophic virus that usually cause mild, self-limiting hand-foot-and-mouth disease (HFMD). However, EV71 infection can sometimes induce a variety of severe neurological complications, pulmonary edema and even death. Here, we aimed to provide an overview of proteomics characterization of EV71-infected brain and lung tissues.

2021-09-10 | PXD023819 | Pride

Structural, biochemical and functional characterization of the essential host factor SETD3 in complex with the enterovirus CV-B3 2A protease

Project description:Enteroviruses cause a number of medically relevant and widespread human diseases with no approved antiviral therapies currently available. We have previously identified the actin histidine methyltransferase SETD3 as critically important for enterovirus infection through a protein-protein interaction with the viral protease 2A. Here, we report the cryo-EM structure of SETD3 in complex with coxsackievirus B3 2A at 3.5 Å resolution. 2A interacts with two distinct interfaces on SETD3, one in the SET domain that overlaps with the actin binding interface, and one in the RSB domain. Structure-function analysis revealed that mutations of key residues in the SET interaction interface resulted in severely reduced binding to 2A and a complete protection from enteroviral infection. Altogether, our findings provide key structural insights into the interaction between SETD3 and 2A and provide a framework for the rational design of host targeted therapeutics against this class of viruses.

2022-10-14 | PXD024127 | Pride

Enterovirus A

Project description:Human enterovirus A overview

| PRJNA69679 | ENA

Enterovirus D68

Project description:Enterovirus D68 Genome sequencing

| PRJNA266569 | ENA

Enterovirus D

Project description:Enterovirus D Genome sequencing

| PRJNA264342 | ENA

Enterovirus B

Project description:Human enterovirus B overview