Dataset Information
Hs-CHPP_LungCancer-Hp-RP-StageTip_H1975
Ontology highlight
ABSTRACT:
REANALYSIS of: PXD002224
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Others
SUBMITTER: Kitata RB, et al.
PROVIDER: PAe005413 | PeptideAtlas | 2015-12-31
REPOSITORIES: PeptideAtlas
Publications
Mining Missing Membrane Proteins by High-pH Reverse-Phase StageTip Fractionation and Multiple Reaction Monitoring Mass Spectrometry.
Journal of proteome research 20150806 9
Despite significant efforts in the past decade toward complete mapping of the human proteome, 3564 proteins (neXtProt, 09-2014) are still "missing proteins". Over one-third of these missing proteins are annotated as membrane proteins, owing to their relatively challenging accessibility with standard shotgun proteomics. Using nonsmall cell lung cancer (NSCLC) as a model study, we aim to mine missing proteins from disease-associated membrane proteome, which may be still largely under-represented. ...[more]
