Proteomics

Dataset Information

0

HUPO Plasma Proteome Project 2 (ProteomExchange)


ABSTRACT: Trauma patients vs Normals, EDTA-plasma, multipeptide proteins and N-glycoproteins

INSTRUMENT(S): LTQ FT, instrument model, Thermo Finnigan instrument model, LTQ, QSTAR

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Wounds And Injuries

SUBMITTER: Matthew Monroe  

PROVIDER: PRD000073 | Pride | 2009-05-15

REPOSITORIES: Pride

Dataset's files

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Publications

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

Liu Tao T   Qian Wei-Jun WJ   Gritsenko Marina A MA   Camp David G DG   Monroe Matthew E ME   Moore Ronald J RJ   Smith Richard D RD  

Journal of proteome research 20051101 6


The enormous complexity, wide dynamic range of relative protein abundances of interest (over 10 orders of magnitude), and tremendous heterogeneity (due to post-translational modifications, such as glycosylation) of the human blood plasma proteome severely challenge the capabilities of existing analytical methodologies. Here, we describe an approach for broad analysis of human plasma N-glycoproteins using a combination of immunoaffinity subtraction and glycoprotein capture to reduce both the prot  ...[more]

Publication: 1/3

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