Dataset Information

Identification of proteins in the venom gland and antennal tissue of a Pogonomyrmex species

ABSTRACT: Not available

OTHER RELATED OMICS DATASETS IN: PRJNA45797

INSTRUMENT(S): instrument model

ORGANISM(S): Pogonomyrmex Rugosus

SUBMITTER: Attila Csordas

PROVIDER: PRD000512 | Pride | 2012-07-26

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	PRIDE_Exp_Complete_Ac_18269.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_18269.pride.mztab.gz	Mztab
	PRIDE_Exp_Complete_Ac_18269.xml.gz	Xml
	PRIDE_Exp_Complete_Ac_18270.pride.mgf.gz	Mgf
	PRIDE_Exp_Complete_Ac_18270.pride.mztab.gz	Mztab

Items per page:

1 - 5 of 6

Publications

Draft genome of the red harvester ant Pogonomyrmex barbatus.

Smith Chris R CR Smith Christopher D CD Robertson Hugh M HM Helmkampf Martin M Zimin Aleksey A Yandell Mark M Holt Carson C Hu Hao H Abouheif Ehab E Benton Richard R Cash Elizabeth E Croset Vincent V Currie Cameron R CR Elhaik Eran E Elsik Christine G CG Favé Marie-Julie MJ Fernandes Vilaiwan V Gibson Joshua D JD Graur Dan D Gronenberg Wulfila W Grubbs Kirk J KJ Hagen Darren E DE Viniegra Ana Sofia Ibarraran AS Johnson Brian R BR Johnson Reed M RM Khila Abderrahman A Kim Jay W JW Mathis Kaitlyn A KA Munoz-Torres Monica C MC Murphy Marguerite C MC Mustard Julie A JA Nakamura Rin R Niehuis Oliver O Nigam Surabhi S Overson Rick P RP Placek Jennifer E JE Rajakumar Rajendhran R Reese Justin T JT Suen Garret G Tao Shu S Torres Candice W CW Tsutsui Neil D ND Viljakainen Lumi L Wolschin Florian F Gadau Jürgen J

Proceedings of the National Academy of Sciences of the United States of America 20110131 14

We report the draft genome sequence of the red harvester ant, Pogonomyrmex barbatus. The genome was sequenced using 454 pyrosequencing, and the current assembly and annotation were completed in less than 1 y. Analyses of conserved gene groups (more than 1,200 manually annotated genes to date) suggest a high-quality assembly and annotation comparable to recently sequenced insect genomes using Sanger sequencing. The red harvester ant is a model for studying reproductive division of labor, phenotyp ...[more]

PMID: 21282651

Similar Datasets

Project description:Venom production has evolved independently many times in the animal kingdom, although it is rare among mammals. Venomous shrews produce venom in their submandibular salivary glands and use it for food acquisition. Only a few toxins have been identified in shrew venoms thus far, and their modes of action require investigation. The biological and molecular processes relating to venom production and gland functioning also remain unknown. To address this gap, we investigated protein content in extracts from venom glands of two shrew species, Neomys fodiens and Sorex araneus, and interpreted their biological functions. Applying a proteomic approach coupled with Gene Ontology enrichment analysis, we identified 313 and 187 putative proteins in venom glands of N. fodiens and S. araneus, respectively. A search of the UniProt database revealed that most of the proteins found in both shrew species were involved in metabolic processes and stress response, while GO enrichment analysis revealed more stress-related proteins in the glands of S. araneus. Molecules that regulate molecule synthesis, cell cycles, and cell divisions are necessary to enable venom regeneration and ensure its effectiveness in predation and food hoarding. The presence of proteins involved in stress response may be the result of shrews' high metabolic rate and the costs of venom replenishment. Some proteins are likely to promote toxin spreading during envenomation and, due to their proteolytic action, reinforce venom toxicity. Finally, finding numerous proteins involved in immune response suggests a potential role of shrew venom gland secretions in protection against pathogens. These findings open up new perspectives for studying biological functions of molecules from shrew venom glands and extend our knowledge on the functioning of eulipotyphlan venom systems. Because the majority of existing and putative venomous mammals use oral venom systems to inject venom into target species, the methods presented here provide a promising avenue for confirming or discovering new taxa of venomous mammals.