Proteomics

Dataset Information

0

Direct evidence of milk consumption from ancient human dental calculus, northern Europe

ABSTRACT: This study investigated the consumption of milk products in the archaeological record, utilizing human dental calculus as a reservoir of dietary proteins from archaeological samples from across Eurasia. Protein extraction and generation of tryptic peptides from dental calculus was performed using a filter-aided sample preparation (FASP) protocol, modified for ancient samples, on 92 samples of archaeological dental calculus. Samples were extracted at three laboratories; the Functional Genomics Centre Zürich (FGCZ), the Centre for GeoGenetics at the National History Museum of Denmark, and BioArCh at the University of York. Sample extracts were sequenced (LC-MS/MS) using an LTQ-Orbitrap Velos (FGCZ), a Q-Exactive Hybrid Quadrupole Orbitrap and an LTQ-Orbitrap Elite (Central Proteomics Facility, Target Discovery Institute, Oxford).

INSTRUMENT(S): LTQ Orbitrap Velos, Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Dental Plaque

SUBMITTER: Jessica Hendy  

LAB HEAD: Matthew Collins

PROVIDER: PXD001361 | Pride | 2015-02-25

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
20120126_23_Z34_N.mgf Mgf
20120126_23_Z34_N.raw Raw
20120126_23_Z34_N_F123069.dat Other
20120330_01_fetuin_40fmol.mgf Mgf
20120330_01_fetuin_40fmol.raw Raw
Items per page:
1 - 5 of 91
altmetric image

Publications

Milk is a major food of global economic importance, and its consumption is regarded as a classic example of gene-culture evolution. Humans have exploited animal milk as a food resource for at least 8500 years, but the origins, spread, and scale of dairying remain poorly understood. Indirect lines of evidence, such as lipid isotopic ratios of pottery residues, faunal mortality profiles, and lactase persistence allele frequencies, provide a partial picture of this process; however, in order to und  ...[more]

Similar Datasets

Proteomics Direct evidence of milk consumption from ancient human dental calculus, northern southwest Asia
2015-02-26 | PXD001359 | Pride
Proteomics Direct evidence of milk consumption from ancient human dental calculus, central Europe
2015-02-25 | PXD001360 | Pride
Proteomics Direct evidence of milk consumption from ancient human dental calculus, UK
2015-02-26 | PXD001362 | Pride
Proteomics Direct evidence of milk consumption from ancient human dental calculus, St Helena
2015-02-25 | PXD001357 | Pride
Proteomics Direct evidence of milk consumption from ancient human dental calculus, central Europe
2017-03-29 | MSV000080765 | MassIVE
Proteomics Direct evidence of milk consumption from ancient human dental calculus, St Helena
2016-07-20 | MSV000079939 | MassIVE
Proteomics Direct evidence of milk consumption from ancient human dental calculus, UK
2016-10-04 | MSV000080221 | MassIVE
Proteomics Direct evidence of milk consumption from ancient human dental calculus, northern southwest Asia
2016-08-18 | MSV000080064 | MassIVE
Proteomics Human dental calculus LC-MS/MS
2014-01-29 | PXD000412 | Pride
Proteomics Human dental calculus LC-MS/MS
2016-10-23 | MSV000080279 | MassIVE