Proteomics

Dataset Information

0

Yeast phosphoproteome - Glucose intake hampers PKA-regulated HSP90 chaperone activity


ABSTRACT: To study the effect of sucrose for yeast phosphoproteome profiling.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

TISSUE(S): Cell Culture

SUBMITTER: Chia-Feng Tsai  

LAB HEAD: Chia-Feng Tsai

PROVIDER: PXD001368 | Pride | 2019-03-18

REPOSITORIES: Pride

Dataset's files

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Publications


Aging is an intricate phenomenon associated with the gradual loss of physiological functions, and both nutrient sensing and proteostasis control lifespan. Although multiple approaches have facilitated the identification of candidate genes that govern longevity, the molecular mechanisms that link aging pathways are still elusive. Here, we conducted a quantitative mass spectrometry screen and identified all phosphorylation/dephosphorylation sites on yeast proteins that significantly responded to c  ...[more]

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