Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA258285PRJNA258215PRJNA258214
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Caenorhabditis Elegans
TISSUE(S): Whole Body
SUBMITTER: Yibo Wu
LAB HEAD: Yibo Wu
PROVIDER: PXD001998 | Pride | 2015-08-06
REPOSITORIES: Pride
Action | DRS | |||
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mir58_MaxQuant_4conditions.zip | Other | |||
target_interact.pep.xls | Xls | |||
uniprot-taxonomy_Caenorhabditis_elegans.fasta | Fasta | |||
ywu_C1309_109.raw | Raw | |||
ywu_C1309_110.raw | Raw |
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Subasic Deni D Brümmer Anneke A Wu Yibo Y Pinto Sérgio Morgado SM Imig Jochen J Keller Martin M Jovanovic Marko M Lightfoot Helen Louise HL Nasso Sara S Goetze Sandra S Brunner Erich E Hall Jonathan J Aebersold Ruedi R Zavolan Mihaela M Hengartner Michael O MO
Genome research 20150731 11
In animals, microRNAs frequently form families with related sequences. The functional relevance of miRNA families and the relative contribution of family members to target repression have remained, however, largely unexplored. Here, we used the Caenorhabditis elegans miR-58 miRNA family, composed primarily of the four highly abundant members miR-58.1, miR-80, miR-81, and miR-82, as a model to investigate the redundancy of miRNA family members and their impact on target expression in an in vivo s ...[more]