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AG3C glucose starvation time course

ABSTRACT: This data set consists of a long term glucose starvation time course of E. coli grown in minimal media for up to two weeks. Unlike previous studies of long term starvation,Our study focuses on the physiological response of E. Coli in stationary phase as a result of being starved for glucose, not on the genetic adaptation of E. coli to utilize alternative nutrients.

OTHER RELATED OMICS DATASETS IN: PRJNA279834

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Escherichia Coli

SUBMITTER: John Houser

LAB HEAD: Claus O. Wilke

PROVIDER: PXD002140 | Pride | 2015-08-24

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	MURI_100_1a_03312014.msf	Msf
	MURI_100_1a_03312014.raw	Raw
	MURI_100_1b_03312014.msf	Msf
	MURI_100_1b_03312014.raw	Raw
	MURI_101_1a_04022014.msf	Msf

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Publications

Controlled Measurement and Comparative Analysis of Cellular Components in E. coli Reveals Broad Regulatory Changes in Response to Glucose Starvation.

Houser John R JR Barnhart Craig C Boutz Daniel R DR Carroll Sean M SM Dasgupta Aurko A Michener Joshua K JK Needham Brittany D BD Papoulas Ophelia O Sridhara Viswanadham V Sydykova Dariya K DK Marx Christopher J CJ Trent M Stephen MS Barrick Jeffrey E JE Marcotte Edward M EM Wilke Claus O CO

PLoS computational biology 20150814 8

How do bacteria regulate their cellular physiology in response to starvation? Here, we present a detailed characterization of Escherichia coli growth and starvation over a time-course lasting two weeks. We have measured multiple cellular components, including RNA and proteins at deep genomic coverage, as well as lipid modifications and flux through central metabolism. Our study focuses on the physiological response of E. coli in stationary phase as a result of being starved for glucose, not on t ...[more]

PMID: 26275208

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