Proteomics

Dataset Information

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Nucleolar proteome of the developing brain


ABSTRACT: To study nucleolar involvement in brain development, the nuclear and nucleolar proteomes from the rat cerebral cortex at postnatal day 7 were analyzed using LC-MS/iTRAQ methodology.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Brain

SUBMITTER: Agata Malinowska  

LAB HEAD: Michal Dadlez

PROVIDER: PXD002188 | Pride | 2016-04-11

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
31015hetamn_P1_03_2.raw Raw
31015hetamn_P1_04_2.raw Raw
31015hetamn_P1_04n_2.raw Raw
31015hetamn_P1_05_2.raw Raw
31015hetamn_P1_06_2.raw Raw
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Publications

Nucleolar Enrichment of Brain Proteins with Critical Roles in Human Neurodevelopment.

Slomnicki Lukasz P LP   Malinowska Agata A   Kistowski Michal M   Palusinski Antoni A   Zheng Jing-Juan JJ   Sepp Mari M   Timmusk Tonis T   Dadlez Michal M   Hetman Michal M  

Molecular & cellular proteomics : MCP 20160406 6


To study nucleolar involvement in brain development, the nuclear and nucleolar proteomes from the rat cerebral cortex at postnatal day 7 were analyzed using LC-MS/iTRAQ methodology. Data of the analysis are available via ProteomeXchange with identifier PXD002188. Among 504 candidate nucleolar proteins, the overrepresented gene ontology terms included such cellular compartmentcategories as "nucleolus", "ribosome" and "chromatin". Consistent with such classification, the most overrepresented funct  ...[more]

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