Dataset Information

Proteome Profiling in Lung Injury Following Hematopoietic Stem Cell Transplantation

ABSTRACT: The goal of this study was to apply protein expression profiling tools in cases with lung injury following HSCT or cellular therapy infusion to identify the proteins and biological processes that differentiate IPS from infectious lung injury in HSCT recipients. We performed comprehensive label-based quantitative protein profiling of BALF in patients undergoing HSCT

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Bronchoalveolar Lavage

DISEASE(S): Adult Respiratory Distress Syndrome

SUBMITTER: Kevin Viken

LAB HEAD: Maneesh Bhargava

PROVIDER: PXD002437 | Pride | 2018-10-24

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	2014_07_14_118_High_Control_PROTEIN_report_for_data_7.tabular	Other
	2014_07_16_117_high_Control_PROTEIN_report_for_data_7.tabular	Other
	2014_07_16_119_high_Control_PROTEIN_report_for_data_7.tabular	Other
	2014_07_16_121_high_Control_PROTEIN_report_for_data_7.tabular	Other
	2014_07_16_High_Control__117PROTEIN_report_for_data_7.tabular	Other

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Publications

Proteome Profiling in Lung Injury after Hematopoietic Stem Cell Transplantation.

Bhargava Maneesh M Viken Kevin J KJ Dey Sanjoy S Steinbach Michael S MS Wu Baolin B Jagtap Pratik D PD Higgins LeeAnn L Panoskaltsis-Mortari Angela A Weisdorf Daniel J DJ Kumar Vipin V Arora Mukta M Bitterman Peter B PB Ingbar David H DH Wendt Chris H CH

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20160505 8

Pulmonary complications due to infection and idiopathic pneumonia syndrome (IPS), a noninfectious lung injury in hematopoietic stem cell transplant (HSCT) recipients, are frequent causes of transplantation-related mortality and morbidity. Our objective was to characterize the global bronchoalveolar lavage fluid (BALF) protein expression of IPS to identify proteins and pathways that differentiate IPS from infectious lung injury after HSCT. We studied 30 BALF samples from patients who developed lu ...[more]

PMID: 27155584

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