Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): B Cell, Bronchoalveolar Lavage, Cell Culture, Macrophage
DISEASE(S): Idiopathic Interstitial Pneumonia,Sarcoidosis,Idiopathic Pulmonary Fibrosis
SUBMITTER: Jimmy Ytterberg
LAB HEAD: Roman A. Zubarev
PROVIDER: PXD002439 | Pride | 2016-08-08
REPOSITORIES: Pride
Action | DRS | |||
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20111214_03_V1_PAT1.raw | Raw | |||
20111214_03_V1_PAT1_Orbimzv2.mgf | Mgf | |||
20130301_03_Q3_PAT2.raw | Raw | |||
20130301_03_Q3_PAT2_Orbimzv2.mgf | Mgf | |||
20130301_04_Q3_PAT3.raw | Raw |
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Heyder Tina T Kohler Maxie M Tarasova Nataliya K NK Haag Sabrina S Rutishauser Dorothea D Rivera Natalia V NV Sandin Charlotta C Mia Sohel S Malmström Vivianne V Wheelock Åsa M ÅM Wahlström Jan J Holmdahl Rikard R Eklund Anders A Zubarev Roman A RA Grunewald Johan J Ytterberg A Jimmy AJ
Molecular & cellular proteomics : MCP 20160724 9
Immune-mediated diseases strongly associating with human leukocyte antigen (HLA) alleles are likely linked to specific antigens. These antigens are presented to T cells in the form of peptides bound to HLA molecules on antigen presenting cells, e.g. dendritic cells, macrophages or B cells. The identification of HLA-DR-bound peptides presents a valuable tool to investigate the human immunopeptidome. The lung is likely a key player in the activation of potentially auto-aggressive T cells prior to ...[more]