Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA326505PRJNA348439PRJNA325307PRJNA326686
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
DISEASE(S): Melanoma
SUBMITTER: Pilar Ximenez-Embun
LAB HEAD: Javier Muñoz Peralta
PROVIDER: PXD003112 | Pride | 2017-12-21
REPOSITORIES: Pride
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Nature communications 20171221 1
Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development remains unclear. Here we identify a cluster of melanoma-enriched genes under the control of CUGBP Elav-like family member 1 (CELF1). CELF1 was discovered with a distinct prognostic value in melanoma after mining the genomic landscape of the 692 known mRBPs across different cancer types. Genome-wide transcriptomic, proteomic, and RNA-immunopr ...[more]