Dataset Information

Molecular profiling of a monkey ischemia stroke model

ABSTRACT: In this study, we examined a Macaca fascicularis transient middle cerebral artery occlusion surgery-induced stroke model, consisting of two sample groups, determined by MRI-quantified infarct volumes as a measure of the stroke severity 28 days after the ischemic episode.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Macaca Fascicularis Fascicularis

TISSUE(S): Brain

DISEASE(S): Cerebrovascular Disease

SUBMITTER: Henry Law

LAB HEAD: Ivan K. Chu

PROVIDER: PXD003173 | Pride | 2017-01-21

REPOSITORIES: Pride

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Publications

Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia.

Law Henry C H HC Szeto Samuel S W SS Quan Quan Q Zhao Yun Y Zhang Zaijun Z Krakovska Olga O Lui Leong Ting LT Zheng Chengyou C Lee Simon M-Y SM Siu K W Michael KW Wang Yuqiang Y Chu Ivan K IK

Journal of proteome research 20170202 3

Stroke is one of the main causes of mortality and long-term disability worldwide. The pathophysiological mechanisms underlying this disease are not well understood, particularly in the chronic phase after the initial ischemic episode. In this study, a Macaca fascicularis stroke model consisting of two sample groups, as determined by MRI-quantified infarct volumes as a measure of the stroke severity 28 days after the ischemic episode, was evaluated using qualitative and quantitative proteomics an ...[more]

PMID: 28102082

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			Action	DRS
	I01.group	Other
	I01_3h_A1_20121208.rar	Other
	I01_MGFPeaklist.mgf	Mgf
	I01_PeptideSummary.txt	Txt
	I01_ProteinSummary.txt	Txt