Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Embryonic Stem Cell, Cell Line Cell
SUBMITTER: HipSci Project
LAB HEAD: Angus Lamond
PROVIDER: PXD003903 | Pride | 2016-06-06
REPOSITORIES: Pride
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Nature 20170510 7658
Technology utilizing human induced pluripotent stem cells (iPS cells) has enormous potential to provide improved cellular models of human disease. However, variable genetic and phenotypic characterization of many existing iPS cell lines limits their potential use for research and therapy. Here we describe the systematic generation, genotyping and phenotyping of 711 iPS cell lines derived from 301 healthy individuals by the Human Induced Pluripotent Stem Cells Initiative. Our study outlines the m ...[more]