Proteomics

Dataset Information

0

Akkermansia muciniphila proteome.


ABSTRACT: Akkermansia muciniphila, a common member of the human gut microbiota, is considered to be a beneficial resident of the intestinal mucus layer. Surface-exposed molecules produced by this organism likely play important roles in colonization and communication with other microbes and the host, but the protein composition of the outer membrane has not been characterized thus far. Herein we identify A. muciniphila proteins after enrichment and fractionation of the outer membrane proteome of A. muciniphila.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Akkermansia Muciniphila Atcc Baa-835

SUBMITTER: Sjef Boeren  

LAB HEAD: Sjef Boeren

PROVIDER: PXD004400 | Pride | 2016-09-27

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
MQ_search_result_NO101-148.zip Other
MQ_search_result_NO111-118.zip Other
NO101_OM_glc.RAW Raw
NO102_OM_glc.RAW Raw
NO103_OM_glc.RAW Raw
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Publications

Characterization of Outer Membrane Proteome of Akkermansia muciniphila Reveals Sets of Novel Proteins Exposed to the Human Intestine.

Ottman Noora N   Huuskonen Laura L   Reunanen Justus J   Boeren Sjef S   Klievink Judith J   Smidt Hauke H   Belzer Clara C   de Vos Willem M WM  

Frontiers in microbiology 20160726


Akkermansia muciniphila is a common member of the human gut microbiota and belongs to the Planctomycetes-Verrucomicrobia-Chlamydiae superphylum. Decreased levels of A. muciniphila have been associated with many diseases, and thus it is considered to be a beneficial resident of the intestinal mucus layer. Surface-exposed molecules produced by this organism likely play important roles in colonization and communication with other microbes and the host, but the protein composition of the outer membr  ...[more]

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