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Across intra-mammalian stages of the liver fluke Fasciola hepatica: a proteomic study

ABSTRACT: Fasciola hepatica is the agent of fasciolosis, a foodborne zoonosis that affects livestock production and human health. Although flukicidal drugs are available, re-infection and expanding resistance to triclabendazole demand new control strategies. Understanding the molecular mechanisms underlying the complex interaction with the mammalian host could provide relevant clues, aiding the search for novel targets in diagnosis and control of fasciolosis.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Fasciola Hepatica (liver Fluke)

SUBMITTER: Itabajara Vaz Jr.

LAB HEAD: Itabajara da Silva Vaz Jr

PROVIDER: PXD004418 | Pride | 2016-09-27

REPOSITORIES: Pride

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			Action	DRS
	20150509_ISV-02_1.raw	Raw
	20150509_ISV-02_1.sepr	Other
	20150509_ISV-02_1.sqt	Other
	20150509_ISV-02_1.txt	Txt
	20150509_ISV-02_2.raw	Raw

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Across intra-mammalian stages of the liver f luke Fasciola hepatica: a proteomic study.

Di Maggio Lucía Sánchez LS Tirloni Lucas L Pinto Antonio F M AF Diedrich Jolene K JK Yates Iii John R JR Benavides Uruguaysito U Carmona Carlos C da Silva Vaz Itabajara I Berasain Patricia P

Scientific reports 20160907

Fasciola hepatica is the agent of fasciolosis, a foodborne zoonosis that affects livestock production and human health. Although flukicidal drugs are available, re-infection and expanding resistance to triclabendazole demand new control strategies. Understanding the molecular mechanisms underlying the complex interaction with the mammalian host could provide relevant clues, aiding the search for novel targets in diagnosis and control of fasciolosis. Parasite survival in the mammalian host is med ...[more]

PMID: 27600774

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