Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Early Embryonic Cell
SUBMITTER: Animesh Sharma
LAB HEAD: Marit Otterlei
PROVIDER: PXD004494 | Pride | 2017-11-23
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
20160504_iPOND_15P_01.raw | Raw | |||
20160504_iPOND_15P_02.raw | Raw | |||
20160504_iPOND_15P_03.raw | Raw | |||
20160504_iPOND_5P_01.raw | Raw | |||
20160504_iPOND_5P_02.raw | Raw |
Items per page: 1 - 5 of 17 |
Nucleic acids research 20170801 14
Base lesions in DNA can stall the replication machinery or induce mutations if bypassed. Consequently, lesions must be repaired before replication or in a post-replicative process to maintain genomic stability. Base excision repair (BER) is the main pathway for repair of base lesions and is known to be associated with DNA replication, but how BER is organized during replication is unclear. Here we coupled the iPOND (isolation of proteins on nascent DNA) technique with targeted mass-spectrometry ...[more]