Proteomics

Dataset Information

0

Pseudomonas aeroginosa resistant against Ciprofloxacin


ABSTRACT: To indentify protein networks and proteins involved in Ciprofloxacin resistance developed by Pseudomonas aeruginosa

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Pseudomonas Aeruginosa Pao1

SUBMITTER: Jianhe Peng  

LAB HEAD: Jianhe Peng

PROVIDER: PXD004560 | Pride | 2016-12-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
0125_MaxQuantOutput.tar.gz Other
05_MaxQuantOutput.tar.gz Other
Pae_025_1_20151107_1.raw Raw
Pae_025_1_20151107_2.raw Raw
Pae_025_1_20151107_3.raw Raw
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Publications

Pseudomonas aeruginosa develops Ciprofloxacin resistance from low to high level with distinctive proteome changes.

Peng Jianhe J   Cao Jing J   Ng Fui Mee FM   Hill Jeffrey J  

Journal of proteomics 20161019


Pseudomonas aeruginosa infection is difficult to treat because of its drug resistance, but how it develops drug resistance remains largely unknown. In this study we investigated Ciprofloxacin resistance development in P. aeruginosa. Different Ciprofloxacin concentrations selected different low level resistant mutants, and high level resistant mutants emerged from low level resistant mutants if stressed further by Ciprofloxacin. A deep quantitative proteomic study of the Ciprofloxacin resistant m  ...[more]

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