Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Hepatocyte, Liver
DISEASE(S): Hepatocellular Carcinoma
SUBMITTER: Tiannan Guo
LAB HEAD: Ruedi Aebersold
PROVIDER: PXD004873 | Pride | 2018-10-31
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
E1603180948_matrix.tsv | Tabular | |||
experiment.properties | Other | |||
guot_L160307_sw_liver1.wiff | Wiff | |||
guot_L160307_sw_liver1.wiff.scan | Wiff | |||
guot_L160307_sw_liver10.wiff | Wiff |
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Proteomics. Clinical applications 20181119 1
<h4>Purpose</h4>To rapidly identify protein abundance changes in biopsy-level fresh-frozen hepatocellular carcinoma (HCC).<h4>Experimental design</h4>The pressure-cycling technology (PCT) is applied and sequential window acquisition of all theoretical mass spectra (SWATH-MS) workflow is optimized to analyze 38 biopsy-level tissue samples from 19 HCC patients. Each proteome is analyzed with 45 min LC gradient. MCM7 is validated using immunohistochemistry (IHC).<h4>Results</h4>A total of 11 787 pr ...[more]