Proteomics

Dataset Information

0

X!Tandem E. coli large vs small database


ABSTRACT: A comparison of the performance when using X!Tandem with a 1) large, exhaustive, reference database; and 2) small, specialized, database.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Escherichia Coli

SUBMITTER: Fredrik Boulund  

LAB HEAD: Edward R. B. Moore

PROVIDER: PXD005924 | Pride | 2017-04-21

REPOSITORIES: Pride

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Publications

Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics.

Boulund Fredrik F   Karlsson Roger R   Gonzales-Siles Lucia L   Johnning Anna A   Karami Nahid N   Al-Bayati Omar O   Åhrén Christina C   Moore Edward R B ERB   Kristiansson Erik E  

Molecular & cellular proteomics : MCP 20170418 6


Methods for rapid and reliable microbial identification are essential in modern healthcare. The ability to detect and correctly identify pathogenic species and their resistance phenotype is necessary for accurate diagnosis and efficient treatment of infectious diseases. Bottom-up tandem mass spectrometry (MS) proteomics enables rapid characterization of large parts of the expressed genes of microorganisms. However, the generated data are highly fragmented, making downstream analyses complex. Her  ...[more]

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